Insomniac Games' Spider-Man titles have not always been the most challenging video games unless players choose one of the higher difficulty modes at the start. Depending on gamers' playstyles, the choice of difficulty will vary; however, many players wonder if a game's difficulty can be changed after selecting it at the start. This guide will show players all the difficulty options for Marvel's Spider-Man 2, go over what each one offers, and whether players have the ability to change it on the fly.